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Blood pressure and the global burden of disease 2000. Part II: Estimates of attributable burden. Commentary

Identifieur interne : 00A070 ( Main/Exploration ); précédent : 00A069; suivant : 00A071

Blood pressure and the global burden of disease 2000. Part II: Estimates of attributable burden. Commentary

Auteurs : Carlene M. M. Lawes [Nouvelle-Zélande] ; Stephen Vander Hoorn [Nouvelle-Zélande] ; Malcolm R. Law [Royaume-Uni] ; Paul Elliott [Royaume-Uni] ; Stephen Macmahon [Australie] ; Anthony Rodgers [Nouvelle-Zélande] ; Francois Gueyffier [France] ; James Wright [Canada]

Source :

RBID : Pascal:06-0212378

Descripteurs français

English descriptors

Abstract

Objectives To provide estimates of the global burden of disease attributable to non-optimal blood pressure by age and sex for adults aged ≥ 30 years, by WHO subregion. Methods Estimates of attributable burden were made using population impact fractions, which used data on mean systolic blood pressure levels, disease burden [in deaths and/or disability-adjusted life years (DALYs)] and relative risk corrected for regression dilution bias. Estimates were made of burden attributable to a population distribution of blood pressure with a mean systolic blood pressure of greater than 115 mmHg. Results Globally, approximately two-thirds of stroke and one-half of ischaemic heart disease were attributable to non-optimal blood pressure. These proportions were highest in the more developed parts of the world. Worldwide, 7.1 million deaths (approximately 12.8% of the global total) and 64.3 million DALYs (4.4% of the global total) were estimated to be due to non-optimal blood pressure. Overall approximately, two-thirds of the attributable burden of disease occurred in the developing world, approximately two-thirds in the middle age groups (45-69 years) and approximately one-half occurred in those with systolic blood pressure levels between 130 and 150 mmHg. Conclusions The burden of non-optimal blood pressure is almost double that of the only previous global estimates, which is largely explained by the correction for regression dilution adopted in these analyses. High blood pressure is a leading cause of global burden of disease, and most of it occurs in the developing world.


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Le document en format XML

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<name sortKey="Gueyffier, Francois" sort="Gueyffier, Francois" uniqKey="Gueyffier F" first="Francois" last="Gueyffier">Francois Gueyffier</name>
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<country>France</country>
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<title level="j" type="main">Journal of hypertension</title>
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<term>Appareil circulatoire pathologie</term>
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<div type="abstract" xml:lang="en">Objectives To provide estimates of the global burden of disease attributable to non-optimal blood pressure by age and sex for adults aged ≥ 30 years, by WHO subregion. Methods Estimates of attributable burden were made using population impact fractions, which used data on mean systolic blood pressure levels, disease burden [in deaths and/or disability-adjusted life years (DALYs)] and relative risk corrected for regression dilution bias. Estimates were made of burden attributable to a population distribution of blood pressure with a mean systolic blood pressure of greater than 115 mmHg. Results Globally, approximately two-thirds of stroke and one-half of ischaemic heart disease were attributable to non-optimal blood pressure. These proportions were highest in the more developed parts of the world. Worldwide, 7.1 million deaths (approximately 12.8% of the global total) and 64.3 million DALYs (4.4% of the global total) were estimated to be due to non-optimal blood pressure. Overall approximately, two-thirds of the attributable burden of disease occurred in the developing world, approximately two-thirds in the middle age groups (45-69 years) and approximately one-half occurred in those with systolic blood pressure levels between 130 and 150 mmHg. Conclusions The burden of non-optimal blood pressure is almost double that of the only previous global estimates, which is largely explained by the correction for regression dilution adopted in these analyses. High blood pressure is a leading cause of global burden of disease, and most of it occurs in the developing world.</div>
</front>
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<name sortKey="Law, Malcolm R" sort="Law, Malcolm R" uniqKey="Law M" first="Malcolm R." last="Law">Malcolm R. Law</name>
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<name sortKey="Macmahon, Stephen" sort="Macmahon, Stephen" uniqKey="Macmahon S" first="Stephen" last="Macmahon">Stephen Macmahon</name>
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<name sortKey="Gueyffier, Francois" sort="Gueyffier, Francois" uniqKey="Gueyffier F" first="Francois" last="Gueyffier">Francois Gueyffier</name>
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<name sortKey="Wright, James" sort="Wright, James" uniqKey="Wright J" first="James" last="Wright">James Wright</name>
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